Endocrinopathies in Thalassemia major patients in Thalassemia Center Jakarta, Indonesia

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Endocrinopathies in Thalassemia major patients in Thalassemia Center Jakarta, Indonesia

Background Regular transfusion in thalassemia major patients increases life expectancy and improves quality of life, but results in iron overload, which had toxic effects to organs including endocrine glands. The introduction of iron chelation therapy has reduced its toxicity, but complications may still occur. In Indonesia, most of our patients did not receive optimal iron chelation therapy, w...

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Prevalence of HCVAb and HBsAg in Patients with Beta-thalassemia Major in Amirkola Thalassemia Center

Background and purpose: Beta-thalassemia major is a genetic disorder with known globin defect that leads to chronic hemolytic anemia. Due to the need for recurrent blood transfusion, the risk of infectious diseases such as hepatitis is higher in these patients. Materials and methods: This cross-sectional study recruited 518 patients with thalassemia major in Amirkola Thalassemia Center, 2013-2...

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Platelet aggregation and activation in thalassemia major patients in Indonesia.

Thromboembolic events and hypercoagulable state have been reported in patients with thalassemia. As platelets play an important role in the pathogenesis of thrombosis, the authors aimed to find the pattern of changes in platelet count, function and activation, and evidence of coagulation activation in patients with thalassemia major in Indonesia. A total of 31 patients with splenectomized and 3...

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Depression and the affecting factors in patients with β Thalassemia Major having referred to Saravan city thalassemia center in 2017

Abstract Background and Objectives The chronic nature of thalassemia affects different aspects of patients' life and increases depression.The goal of the study was to determine depression and the affecting factors in patients with thalassemia major reffered to Saravan thalassemia center.   Materials and Methods The population of this descriptive analytic study consisted of 60 thalassemic pat...

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Endocrine Disorders in Beta thalassemia Major Patients

Background Thalassemia is the most common hereditary disorder worldwide. The patient's’ survival is dependent on lifetime blood transfusion which leads to iron overload and its toxicity on various organs including endocrine glands. The study aimed to investigate endocrine disorders in patients with Beta-thalassemia major in the Southern Khorasan province, Iran. Materials and Methods In this des...

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ژورنال

عنوان ژورنال: International Journal of Pediatric Endocrinology

سال: 2013

ISSN: 1687-9856

DOI: 10.1186/1687-9856-2013-s1-p58